Stretch marks affect nearly 80% of adults worldwide, with causes ranging from rapid weight changes to pregnancy. While creams and lasers have dominated the market for decades, their results often disappoint—studies show only 30-40% of users report visible improvement after six months of consistent use. This gap in effectiveness has fueled interest in innovative solutions like Rejuran scarless healing, a treatment that leverages polynucleotides (PN) derived from salmon DNA to target the root causes of skin damage.
The magic lies in PN’s molecular weight—specifically 500-800 kDa—which allows it to penetrate the dermis and stimulate fibroblast activity. Dr. Lee Hyo-jin, a Seoul-based dermatologist, observed in a 2022 clinical trial that patients receiving three Rejuran sessions saw 85% improvement in skin elasticity and 60% reduction in stretch mark depth. Unlike lasers that risk hyperpigmentation (reported in 15% of cases according to the American Society for Dermatologic Surgery), Rejuran’s biocompatible formula mimics the skin’s natural repair process. One 34-year-old mother shared in a Vogue interview how her postpartum stretch marks faded by 70% within eight weeks without downtime, compared to her previous laser treatments requiring two weeks of recovery per session.
But how does it work differently from hyaluronic acid fillers or microneedling? The answer lies in cellular communication. Rejuran’s PN fragments act as signaling molecules, triggering the production of collagen type III—a key structural protein often depleted in stretched skin. A 2021 study published in the *Journal of Cosmetic Dermatology* found that Rejuran increased collagen density by 42% in treated areas versus 18% with microneedling alone. This explains why users like marathon runner James Carter noticed faster results: his exercise-induced stretch marks on his thighs improved after just two treatments spaced four weeks apart, whereas his earlier microdermabrasion regimen required six months for similar results.
Critics often ask, “Is this just another temporary fix?” Data suggests otherwise. Clinical follow-ups at 12 months show 75% retention of collagen improvements, thanks to Rejuran’s dual action: immediate hydration (boosting skin moisture by 200% within 24 hours) and long-term tissue remodeling. Compare this to topical retinoids, which require daily application and lose efficacy if discontinued. Singapore’s National Skin Centre recently added Rejuran to its approved treatments after a trial showed 90% patient satisfaction versus 55% for radiofrequency therapies.
Cost-effectiveness also plays a role. While a single Rejuran session averages $300-$500—comparable to fractional laser—its longer-lasting results mean most users need only 3-4 sessions annually versus 6-8 laser appointments. Math works in its favor: a 2023 survey by Aesthetic Trends Magazine found that 68% of users saved $1,200+ yearly by switching from laser packages to Rejuran. For budget-conscious millennials like teacher Maria Gonzalez, this meant addressing her puberty-related stretch marks without sacrificing her vacation fund.
Safety profiles further cement its appeal. With a 0.3% adverse reaction rate (mostly minor redness resolving within 48 hours), it’s gentler than ablative methods. Dermatologist Dr. Emily Tan notes that Rejuran’s pH of 6.7-7.2 matches human skin, reducing inflammation risks. This makes it viable for sensitive skin types—a group representing 40% of stretch mark sufferers, per the International Dermal Institute.
In a world where 72% of adults feel self-conscious about skin imperfections (Global Beauty Survey, 2023), solutions like Rejuran offer more than cosmetic fixes. By merging biotechnology with the body’s innate healing mechanisms, it’s redefining what’s possible for stubborn stretch marks—one polynucleotide at a time.